A sign has the potential to be objectively observed by someone other than the patient, whereas a symptom does not. There is a correlation between this difference and the difference between the medical history and the physical examination . Symptoms belong only to the history, whereas signs can often belong to both. Clinical signs such as rash and muscle tremors are objectively observable both by the patient and by anyone else. Some signs belong only to the physical examination, because it takes medical expertise to uncover them. (For example, laboratory signs such as hypocalcaemia or neutropenia require blood tests to find.) A sign observed by the patient last week but now gone (such as a resolved rash) was a sign, but it belongs to the medical history, not the physical examination, because the physician cannot independently verify it today.
Hepatic Lipidosis Most common form of severe liver disease in cats. Most often seen in obese cats suddenly subjected to dietary deprivation. May also be associated with diabetes mellitus, drug injury and toxicity. Thedisease seems to result from the sudden mobilisation of the bodies fat stores which quickly overwhelms the liver's ability to process the raw fat into useful nutrients. The fat accumulates in the liver rapidly and causes acute liver failure. The end result is a swollen, greasy liver which is fragile and yellow to see. The cats present with complete lack of appetite and many signs of acute liver failure. Treatment is based on the provision of a highly nutritious diet to provide the energy required to run the body, stop the ongoing mobilisation of the fat stores, and drive the liver to decrease the fatty accumulation in the liver. Treatment is difficult and a long process.
Ovarian cancer has been coined the "silent killer" as symptoms often occur late in the disease, and then are frequently dismissed as due to something else. It's been found that bloating is a common symptom of ovarian cancer, but women often attribute this symptom to weight gain or other causes. Likewise, constipation, pain with intercourse, constipation, and frequent urination can be symptoms of ovarian cancer but are often first attributed to other causes. If you notice any of these symptoms talk to your doctor. Ovarian cancer can be curable when caught early.