The most distinctive aspect of this tragic case was the finding of markedly atrophied adrenal glands, something not seen before in an otherwise athletic person. The authors suggest that the shrinkage may have occurred because of her extensive anabolic steroid use. Steroids interfere with the activity of cortisol, which is considered desirable because cortisol is catabolic. On the other hand, long-term, heavy use of anabolic steroids could have sent an inhibitory signal to the pituitary gland, which responded by not secreting adrenocorticotropic hormone, which tells the adrenal glands to synthesize and secrete cortisol. No ACTH, no cortisol or even DHEA release. When that happens, the adrenals shrivel up. The same occurs in the testicles when large doses of anabolic steroids are used. In that case the pituitary stops secreting luteinizing hormone, resulting in no testosterone production in the testes—hence shrunken testicles.
For one reason or another many people believe some anabolic androgenic steroids do not suppress testosterone and this simply isn't so. It is true, the level of suppression varies with each form; for example, Deca-Durabolin will suppress production completely after one dose, while milder steroids such as Anavar only suppress slightly but slightly is still suppression. In our case here, one of the often forgotten Dianabol side effects is in-fact testosterone suppression. It will not suppress to the degree of Nandrolone or Trenbolone but it is more than enough to warrant a need for exogenous testosterone therapy .
A-Rod, Lance Armstrong, Jose Canseco, Rashard Lewis, Shawne Merriman. The list of superstar athletes accused of -- or admitting to -- taking performance-enhancing drugs is almost as impressive as the number of sports in which they compete. It's not just weightlifting, baseball and cycling. It's football, track and field, swimming, soccer and basketball . And it's not restricted to males -- or to professionals. Just ask former Olympic track star Marion Jones. Or the nine high school athletes in Texas caught using performance-enhancing drugs during the 2011-2012 academic year.