Male sexual hormones

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Treatment for proven androgen deficiency is based on testosterone replacement therapy. Testosterone can be administered by capsule or tablet, skin patch, gel, lotion or cream, or injection (short- or long-acting). 

If the cause of testosterone deficiency is located in the pituitary gland, and the man is also wishing to father a child, then gonadotrophin injections, several times a week for many months, are used to stimulate both testosterone and sperm production.

Men who receive testosterone replacement therapy will have regular reviews with their doctor. Prostate examinations are performed according to a man's age and other risk factors for prostate cancer. 

Older men need to be checked for prostate cancer before testosterone replacement therapy can be started, because increased levels of testosterone could make unrecognised prostate cancer grow. However, testosterone replacement therapy is not thought to increase the risk of a new prostate cancer above that of the general population.

Neural injections of Bromodeoxyuridine (BrdU) were applied to males of both groups to test for neurogenesis . Analysis showed that testosterone and dihydrotestosterone regulated adult hippocampal neurogenesis (AHN). Adult hippocampal neurogenesis was regulated through the androgen receptor in the wild-type male rats, but not in the TMF male rats. To further test the role of activated androgen receptors on AHN, flutamide , an antiandrogen drug that competes with testosterone and dihydrotestosterone for androgen receptors , and dihydrotestosterone were administered to normal male rats. Dihydrotestosterone increased the number of BrdU cells, while flutamide inhibited these cells.

Some research has suggested that testosterone produced by the sex organs in males and the adrenal glands (on top of the kidneys) in females, has less to do with whether a man will become sexually aroused than is widely believed. Other recent research suggests that it is not testosterone, but a compound closely related to testosterone that is important. Ordinarily, after ejaculation, a man has no further interest in sexual activity of any kind. For a period of 10 minutes to perhaps more than an hour, or even days for older men. During this refractory period a man is physically unable to achieve another orgasm even if he is able to maintain  erection.

Male sexual hormones

male sexual hormones

Some research has suggested that testosterone produced by the sex organs in males and the adrenal glands (on top of the kidneys) in females, has less to do with whether a man will become sexually aroused than is widely believed. Other recent research suggests that it is not testosterone, but a compound closely related to testosterone that is important. Ordinarily, after ejaculation, a man has no further interest in sexual activity of any kind. For a period of 10 minutes to perhaps more than an hour, or even days for older men. During this refractory period a man is physically unable to achieve another orgasm even if he is able to maintain  erection.

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