Researchers from Monash University in Melbourne and the University of South Australia in Adelaide tested two different doses of the testosterone cream product known as AndroFeme (5 mg and 10 mg doses). After 21 days of daily administration, the 5-mg dose brought postmenopausal women's peak blood levels of total testosterone right into the normal premenopausal range -- with a peak slightly above the upper limit of the premenopause normal and 24-hour average to slightly below the limit. The 10-mg dose raised testosterone levels to a higher peak but only somewhat higher than the norm (50%) over 24 hours.
Clinical research still hasn’t determined a hard threshold level for when symptoms of low T begin appearing . Some recent research suggests that symptoms of low T might begin appearing in men when their total testosterone level dips below 320 ng/dl . According to anecdotal evidence from the owner of Peak Testosterone, many men start noticing low T symptoms when their total testosterone dips into the 400s . Of course, it’s anecdotal, so take it for what it’s worth, but it’s probably a good idea to stay above 500 ng/dl if you don’t want to experience symptoms of low T.